AQUA 40.00 Vario and Vario PLUS
Precise Moisture Analysis Made Simple

Product description
The AQUA 40.00 Vario combines the trusted Karl Fischer titration method with dynamic headspace technology, offering a wide range of exciting applications. It enables accurate moisture determination in solids, semi-solid samples, oils, and highly viscous substances.
Sample preparation is quick and straightforward:
the sample is sealed in a vial and precisely tempered in the headspace oven. A closed-loop system with dry carrier gas then flows over the sample, transporting the extracted moisture completely into the measuring cell, where the analysis is performed using Karl Fischer titration.
Your advantages: No complex sample preparation required
- Weigh the sample into a headspace vial and seal it
- Place the vial into the device (manually or automatically)
- Start the measurement – that’s it
Fast, clean, and efficient – the AQUA 40.00 Vario delivers maximum precision with minimal effort.

Aqua 40.00 Vario PLUS

Standard Conformity
The coulometric Karl Fischer titrator AQUA 40.00 Vario/Vario PLUS can be used for the following standard methods:
ASTM D 1364, ASTM D 1533, ASTM D 3401, ASTM D 4928, ASTM D 6304, ASTM D 6869, ASTM E 1064, API Ch. 10.9, DIN 51777, DIN EN 60814,
DIN EN ISO 12937, EI /IP 386, EI / IP 438, ISO 10337

Applications
- Pharmaceutical products
- Biological substances
- Plastics
- Hygroscopic compounds
- Freeze-dried products, e. g. lyophilized cultures
- Oils and lubricants, creams, pastes
- Viscous materials (bitumen, tar, sludges)
- Powder and pellets
- Food
- Petrochemicals

Aqua 40.00 Vario

Advantages
- Reduced reagent consumption
- No evaporation of methanol from the reagent
- Additional gas drying is not required due to closed-loop circulation of extraction gas
- Stand-by titration for automatic conditioning and
- Easy blank tests
- Short measuring times, even with complicated samples
- Suitable for 2 R to 50 R vials
- Easy automation with autosampler

Features and Results
- Configurable temperature programmes
- Automatic identification of interchangeable oven and sample plate of the autosampler
- Priorized express samples can set individually by user
- Software complies with requirements of FDA to 21 CFR Part 11 (Software with user-specific access, routine methods for individual and definable user levels, profound documentation and archiving of all measured data

Software requirements
Operating system | Windows 10 or higher |
Platform | 32 Bit (x86) |
CPU | 1 Ghz |
RAM | 1 GB |
HDD / SSD | 17 GB |
GPU | DirectX 9 with WDDM 1.0 |
Available languages | German, English |
Number of connections | 1 |
Data connection | RS 232 or USB-Hub |

Typical measurement with isothermal heating

Measurement with temperature programme to distinguish of adsorbed and bound water

Technical specifications
for Aqua 40.00 Vario Plus
Device Type | Expansions module |
Power supply | 230 V/60 Hz or 110 V/60 Hz |
Power input | 250 W |
Dimensions (L x H x D) | 420 x 450 x 460 mm |
Weight | 17 kg |
Data connection | RS 232 |
Device control | PC Software |
Sample dosing | Headspace vials (size 2 R to 50 R) |
Measuring range | 1 µg to 100 mg absolute |
Resolution | 0.1 µg |
Reproducibility | ± 3 µg for 10 to 1000 µg, 3 % for over 1 mg |
Temperature range | 35 °C to 300 °C (isothermal or with temperature programme) |

Technical specifications
for Aqua 40.00 Vario
Device Type | Expansions module |
Power supply | 230 V/50 Hz or 110 V/50 Hz |
Power input | 250 W |
Dimensions (L x H x D) | 300 x 450 x 240 mm |
Weight | 7 kg |
Data connection | RS 232 |
Device control | PC Software |
Sample dosing | Headspace vials (size 2 R to 50 R) |
Measuring range | 1 µg to 100 mg absolute |
Resolution | 0.1 µg |
Reproducibility | ± 3 µg for 10 to 1000 µg, 3 % for over 1 mg |
Temperature range | 35 °C to 300 °C (isothermal or with temperature programme) |